Growth Peptides

    IGF1-LR3 (1mg)

    4.9 (31 reviews)
    99%+ Pure

    IGF-1 LR3 is a modified version of insulin-like growth factor 1 with an extended half-life. The LR3 modification involves substitution of Arg for Glu at position 3 and an N-terminal extension of 13 amino acids, significantly reducing binding to IGF-binding proteins. This results in enhanced bioavailability and potency for growth and anabolic research.

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    Third-Party Tested
    Cold-Chain Shipped
    Research Grade
    Discreet Packaging

    Specifications

    Molecular Weight
    9111.4 g/mol
    Form
    Lyophilized Powder
    Storage
    -20°C
    Purity
    99%+
    Solubility
    Soluble in 0.1M acetic acid

    Amino Acid Sequence

    Modified IGF-1 with N-terminal 13aa extension + Arg3 substitution

    Research Areas

    Muscle Growth Cell Proliferation Anabolic Pathways Recovery

    Frequently Asked Questions

    What is IGF1-LR3 (1mg) and what is it used for in research?
    IGF-1 LR3 is a modified version of insulin-like growth factor 1 with an extended half-life. The LR3 modification involves substitution of Arg for Glu at position 3 and an N-terminal extension of 13 amino acids, significantly reducing binding to IGF-binding proteins. This results in enhanced bioavailability and potency for growth and anabolic research. It is classified under the Growth Peptides research category and is studied in the following areas: Muscle Growth, Cell Proliferation, Anabolic Pathways, Recovery.
    What is the purity of IGF1-LR3 (1mg)?
    Our IGF1-LR3 (1mg) is tested at 99%+ purity via third-party HPLC analysis. Every order ships with a Certificate of Analysis (COA) documenting purity, identity, and endotoxin levels.
    How should IGF1-LR3 (1mg) be stored?
    IGF1-LR3 (1mg) should be stored at -20°C. It is supplied as a lyophilized powder and is soluble in 0.1m acetic acid.
    What is the mechanism of action of IGF1-LR3 (1mg)?
    IGF-1 receptor agonist with reduced IGF-binding protein affinity; activates PI3K/Akt and MAPK/ERK pathways promoting cell proliferation and protein synthesis
    What is the molecular weight and sequence of IGF1-LR3 (1mg)?
    IGF1-LR3 (1mg) has a molecular weight of 9111.4 g/mol. Its amino acid sequence is: Modified IGF-1 with N-terminal 13aa extension + Arg3 substitution.
    Does IGF1-LR3 (1mg) come with a Certificate of Analysis?
    Yes. Every batch of IGF1-LR3 (1mg) is third-party tested and ships with a full Certificate of Analysis (COA) documenting HPLC purity, mass spectrometry identity confirmation, and endotoxin testing results.
    What is the half-life of IGF1-LR3 (1mg)?
    20-30 hours (extended vs. native IGF-1 due to reduced IGFBP binding)
    What delivery methods are used with IGF1-LR3 (1mg) in research?
    In published research, IGF1-LR3 (1mg) has been administered via subcutaneous injection, intramuscular injection. All use is for laboratory research purposes only.

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    Research Use Only: This product is intended for laboratory research purposes only. Not for human consumption, veterinary use, or any clinical/therapeutic applications.