Stable gastric pentadecapeptide BPC 157 can improve the healing course of spinal cord injury and leads to functional recovery in rats
Perovic D, Kolenc D, Bilic V, et al.
Journal of Orthopaedic Surgery and Research
Summary
Investigated the neuroprotective effects of BPC 157 in a rat spinal cord injury model. Treated animals showed significant functional recovery and improved histological outcomes, expanding BPC 157 research beyond musculoskeletal applications.
Key Findings
- BPC 157-treated rats showed significantly better locomotor recovery scores (BBB scale)
- Histological analysis revealed less tissue necrosis and better neural preservation
- Both intraperitoneal and per-oral administration routes were effective
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DOI: 10.1002/jor.21107