Regulation of growth hormone secretion by growth hormone-releasing peptide-6 (GHRP-6)
Micic D, Popovic V, Doknic M, et al.
Journal of Pediatric Endocrinology
Summary
Early clinical characterization of GHRP-6 as a potent growth hormone secretagogue in humans. Demonstrated that GHRP-6 stimulates GH release through a mechanism distinct from GHRH, and that combined administration produces synergistic GH responses.
Key Findings
- GHRP-6 potently stimulated GH release in human subjects
- Mechanism of action distinct from growth hormone-releasing hormone (GHRH)
- Synergistic GH response observed when GHRP-6 combined with GHRH
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DOI: 10.1042/CS20050374