Pharmacology
Dose-Response Curve
Definition
A dose-response curve is a graphical representation of the relationship between the amount of a substance administered and the magnitude of its biological effect. The curve typically follows a sigmoidal shape, with key parameters including the EC50 (half-maximal effective concentration), the maximum response (Emax), and the Hill coefficient describing cooperativity. Dose-response relationships are fundamental to establishing effective research concentrations for peptides.